Laboratoř struktury a funkce proteinů

The Laboratory of Structure and Function of Proteins is a joint laboratory of the Center for Nanobiology and Structural Biology, Institute of Microbiology, Academy of Sciences the Czech Republic and the Faculty of Sciences.

The relationship between structure and function of proteins and their complexes is the central research topic, and therefore the laboratory combines methods ranging from computational (Molecular dynamics, quantum chemical and semiempiric calculations, charge localisation or energy transfer and molecular modelling methods) and spectroscopic, to molecular biological, biochemical, and in collaboration with the Kuta Smatanova lab protein crystallisation.With its focus on molecular systems biology, the relationship between structure and function of proteins, dynamic changes related to functional processes on the level of proteins and the mutual interaction of cofactors and subunits in protein complexes the laboratory is on the forefront of current protein science. The laboratory has highly ambitious aims with regard to the development of new methods in molecular systems biology and its application to systems of a common interest, hot topic systems.

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